Example 1

Two colorectal cancers, one exhibiting a BRAF V600E mutation and both with a double hit in TP53 and APC genes (samples analysed by TCGA)

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Example 2

Chronic lymphocytic leukemia with a NOTCH nonsense mutation (exome sequenced by the Broad Institute)

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Example 3

Non-small cell lung cancer with a EGFR activating mutation (exome sequenced by TCGA)

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Example 4

Bladder carcinoma exhibiting CDKN2 deletions and FGFR3-TACC3 fusion gene (exome sequenced by TCGA)

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