Cancer Genome Interpreter - Identification of therapeutically actionable genomic alterations in tumors

March 2024: ClinVar and CIViC databases have been updated to include recent data releases

Alterations

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Cancer type

(CANCER) Any cancer type
- (HEMATO) Hematologic malignancies
  - (LK) Leukemia
    - (LL) Lymphoblastic leukemia
      - (ALL) Acute lymphoblastic leukemia
        
        (TCALL) T-cell acute lymphoblastic leukemia
    - (MKB) Megakaryoblastic leukemia
    - (MML) Myelomonocyitic leukemia
    - (TCPL) T-cell prolymphocytic leukemia
    - (AEL) Acute erythroid leukemia
    - (AML) Acute myeloid leukemia
    - (APML) Acute promyelocytic leukemia
    - (CLL) Chronic lymphocytic leukemia
    - (CNL) Chronic neutrophilic leukemia
    - (HCL) Hairy-Cell leukemia
    - (LGLK) Large granular leukemia
    - (CML) Chronic myeloid leukemia
      - (ACML) Atypical chronic myeloid leukemia
    - (ECL) Eosinophilic chronic leukemia
  - (LY) Lymphoma
    - (MCL) Mantle cell lymphoma
    - (MUCLY) Mucosa-associated lymphoma
    - (NHLY) Non-hodking lymphoma
      - (PTCL) Perypheral T-cell lymphoma
      - (NKTL) Extranodal natural killer/T-cell lymphoma
      - (SLL) Small lymphocytic lymphoma
      - (MALT) MALT lymphoma
    - (THYM) Thymic
    - (ALCL) Anaplastic large cell lymphoma
    - (BCL) B cell lymphoma
      - (LBCL) Large B-Cell lymphoma
        
        (DLBCL) Difuse large B Cell lymphoma
      - (LPL) Lymphoblastic lymphoma
        
        (WM) Waldenström macroglobulinemia
    - (BLY) Burkitt lymphoma
    - (CTCL) Cutaneous T-cell lymphoma
    - (FL) Follicular lymphoma
    - (HLY) Hodking lymhpoma
    - (CNSLY) Central nervous system lymphoma
  - (MAS) Mastocytosis
    - (MCLK) Mast cell leukemia
    - (SM) Systemic mastocytosis
  - (MDS) Myelodisplasic syndrome
    - (MDPS) Myelodisplasic proliferative syndrome
  - (MYMA) Myeloma
    - (MM) Multiple myeloma
  - (CMP) Chronic myeloproliferitve neoplasm
    - (MY) Myelofibrosis
      - (IM) Inflammatory myofibroblastic
    - (PV) Polycitemia vera
    - (ECL) Eosinophilic chronic leukemia
  - (EOS) Eosinophilia
    - (HES) Hyper eosinophilic advanced snydrome
    - (ECL) Eosinophilic chronic leukemia
- (SOLID) Solid tumors
  - (TX) Torax
    - (BRCA) Breast adenocarcinoma
      - (BRCAL) Breast lobular
      - (BRCADC) Breast ductal
      - (BRCAMDLC) Breast mixed ductal and lobular
    - (L) Lung
      - (LAM) Lymphangioleiomyomatosis
      - (NSCLC) Non-small cell lung
        
        (LUAD) Lung adenocarcinoma
        
        (LUSC) Lung squamous cell
      - (PPB) Pleuropulmonary blastoma
      - (SCLC) Small cell lung
    - (MESO) Mesothelioma
      - (PLMESO) Pleural mesothelioma
    - (PL) Pleura
      - (PPB) Pleuropulmonary blastoma
  - (US) Urinary system
    - (UTC) Urinary tract carcinoma
    - (UTH) Urothelial
      - (UTUC) Upper tract urothelial carcinoma
    - (BLCA) Bladder
      - (BLTC) Bladder transitional cell
    - (R) Renal
      - (RA) Renal angiomyolipoma
      - (RCCC) Renal clear cell
      - (RCH) Renal chromophobe cell
      - (RPC) Renal papillary cell
      - (WT) Wilms tumor
  - (DS) Digestive system
    - (DT) Digestive tract
      - (ESCA) Esophagous
        
        (ESA) Esophagous adenocarcinoma
        
        (ESSC) Esophagous squamous cell
      - (FAP) Familial adeno poliposis
      - (GIST) Gastrointestinal stromal
      - (OC) Oral cavity
        
        (OCSC) Oral cavity squamous cell
        
        (SG) Salivary glands
        
        (SGA) Salivary glands adenoma
        
        (SGM) Salivary glands mucoepidermoid
        
        (ADCC) Adenoid cystic carcinoma
        
        (MYEP) Myoepithelioma
        
        (TOSC) Tongue squamous cell
      - (OPH) Ororpharynx squamous cell
      - (PAMP) Periampullary adenoma
      - (REC) Rectal carcinoma
      - (SIN) Small intestine
        
        (SINNE) Small intestine neuroendocrine
      - (ST) Stomach
        
        (STAD) Stomach adenocarcinoma
        
        (GEJA) Gastroesophageal junction adenocarcinoma
      - (COC) Colon carcinoma
        
        (COCA) Colon adenocarcinoma
      - (COREAD) Colorectal adenocarcinoma
      - (READ) Rectal adenocarcinoma
    - (LVB) Liver & billiary tract
      - (BT) Billiary tract
      - (CH) Cholangiocarcinoma
        
        (IHCH) Intrahepatic cholangiocarcinoma
      - (H) Hepatic
        
        (HA) Hepatic adenoma
        
        (HB) Hepatic blastoma
        
        (HC) Hepatic carcinoma
    - (NSPH) Nasopharyngeal
  - (ES) Endocrine System
    - (PA) Pancreas
      - (PAAD) Pancreas adenocarcinoma
        
        (PAAC) Pancreas acinar
      - (PAIS) Pancreas neuroendocrine
    - (PARG) Paraganglioma
    - (PATH) Parathyroid adenoma
    - (PIGA) Pituitary gland adenoma
    - (TH) Thyroid
      - (THA) Thyroid adenoma
      - (THCA) Thyroid carcinoma
        
        (THF) Thyroid follicular
        
        (THM) Thyroid medullary
      - (THP) Thyroid papillary
    - (AG) Adrenal gland
      - (AA) Adrenal adenoma
      - (AC) Adrenal cortex
        
        (ACA) Adrenal cortex adenoma
        
        (ACC) Adrenal cortex carcinoma
  - (FRS) Female reproductory system
    - (OV) Ovary
      - (OVCC) Ovary clear cell
      - (OVE) Ovary epithelial cell
      - (OVG) Ovary granulosa cell
      - (OVSC) Ovary small cell
      - (OVSE) Ovary serous
      - (FGCT) Female germ cell tumor
      - (OVRT) Ovary rhabdoid tumor
      - (SCGS) Sex-cord gonadal stromal
        
        (LEY) Leydig cell adenoma
    - (U) Uterus
      - (UCS) Uterine carcinosarcoma
      - (ED) Endometrium
        
        (EDA) Endometrial adenocarcinoma
        
        (EDS) Endometrial stromal
        
        (UCEC) Uterine corpus endometroid carcinoma
      - (ULMS) Uterine leiomyosarcoma
    - (CER) Cervix
      - (CESC) Cervix squamous cell
  - (HNC) Head an neck
    - (HNSC) Head an neck squamous
  - (MRS) Male reproductory system
    - (PRAD) Prostate adenocarcinoma
    - (T) Testis
      - (MGCT) Male germ cell tumor
        
        (NSMGCT) Non-seminomatous germ cell tumor
        
        (TER) Teratoma
        
        (SMGCT) Seminomatous germ cell tumor
        
        (MMGCT) Mixed germ cell tumor
  - (MSKV) Musculoskeletal & vascular systems
    - (MYX) Myxoma
    - (NMC) NUT midline carcinoma
    - (S) Sarcoma
      - (STS) Soft tissue sarcoma
      - (SYNS) Synovial sarcoma
      - (AS) Angiosarcoma
      - (CCS) Clear cell sarcoma
      - (CS) Chondrosarcoma
      - (DFS) Dermatofibrosarcoma
      - (DSRCT) Desmoplastic small round cell tumor
      - (EWS) Ewing sarcoma
      - (FIBS) Fibrosarcoma
      - (HIS) Histiocytoma
        
        (HISEC) Erdheim-Chester histiocytosis
        
        (HISLC) Langerhans cell histiocytosis
        
        (MFH) Myxoidfibrosarcoma
        
        (FH) Fibrous histiocytoma
      - (LEIS) Leiomyosarcoma
        
        (ULMS) Uterine leiomyosarcoma
      - (LIP) Liposarcoma
        
        (DLIP) Dedifferentiated liposarcoma
      - (MRT) Malignant rhabdoid tumor
        
        (OVRT) Ovary rhabdoid tumor
        
        (RHBDS) Rhabdomyosarcoma
      - (OS) Osteosarcoma
      - (RHBDS) Rhabdomyosarcoma
    - (ABC) Aneurysmal bone cyst
    - (DEST) Desmoid tumor
    - (HGP) Hemangiopericytoma
  - (NEU) Neuroendocrine
    - (PAIS) Pancreas neuroendocrine
    - (SINNE) Small intestine neuroendocrine
  - (NS) Nervous system
    - (PNS) Peripheral nervous system
      - (SCHW) Schwannoma
      - (MPN) Malignant peripheral nerve sheat tumor
      - (NB) Neuroblastoma
      - (NF) Neurofibroma
      - (PLEN) Plexiform neurofibroma
    - (SS) Sensory system
      - (EY) Eye
        
        (RB) Retinoblastoma
        
        (UVM) Uveal melanoma
    - (CNS) Central nervous system
      - (CNSLY) Central nervous system lymphoma
      - (DNT) Dysembryoplastic neuroepithelial tumour
      - (G) Glioma
        
        (GB) Glioblastoma
        
        (GBM) Glioblastoma multiforme
        
        (LGG) Lower grade glioma
        
        (MA) Malignant astrocytoma
        
        (PIA) Pilocityc astrocytoma
        
        (APA) Anaplastic astrocytoma
        
        (GCA) Giant cell astrocytoma
        
        (PG) Pediatric glioma
        
        (AOG) Anaplastic oligodendroglioma
        
        (PHEO) Pheochromocytoma
        
        (PCPG) Pheochromocytoma and paraganglioma
      - (MB) Medulloblastoma
      - (MEN) Meningioma
      - (B) Brain
  - (SK) Skin
    - (ALM) Acral lentigious melanoma
    - (BCC) Basal cell carcinoma
    - (CM) Cutaneous melanoma
    - (DFS) Dermatofibrosarcoma
    - (MERC) Merkel cell carcinoma
    - (MUCM) Mucosal melanoma
    - (PEC) Perivascular epithelioid cell
    - (SCC) Squamous cell carcinoma

Reference genome

hg38

hg19

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